If the global response against HIV/AIDS as a public threat remains unchanged, we will not attain the transformative goal of ending AIDS and meeting the 2030 Agenda for sustainable development. As young people and key populations are increasingly becoming the face of the epidemic, this session will look into how we can change the trajectory of the global HIV/AIDS response to meet prevention and treatment targets and adopt a truly rights-based approach that leaves no one behind. Representatives from young people and key populations, as well as global leaders and experts, will share their experiences and discuss the best way to ensure inclusive, effective and transformative HIV/AIDS response.